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    excellness弹性细胞培养板,excellness弹性细胞培养皿
    • excellness弹性细胞培养板,excellness弹性细胞培养皿

    excellness弹性细胞培养板,excellness弹性细胞培养皿

    产品报价:询价

    更新时间:2019/2/15 13:57:39

    地:荷兰

    牌:excellness

    号: excellness

    厂商性质: 生产型,贸易型,服务型,

    公司名称: 北京容圣科技有限公司

    产品关键词: 仿生细胞培养底物   仿生细胞培养环境   excellness   弹性细胞培养皿   弹性细胞培养板  

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    PrimeCoat series

    The ExCellness PrimeCoat series is designed specifically to provide a biomimetic cell culture environment that improves cell characteristics and phenotype in laboratory applications.
    Picture
    Key features
    • PrimeCoat elastic substrates are easy to use for cell culture and subsequent analysis.

    • PrimeCoat elastic substrates are available with 6 degrees of softness within the elasticity range of body tissues: 2, 5, 10, 15, 30 and 100 kPa.

    • PrimeCoat elastic substrates are available in 4 standard formats: 100 mm diameter dishes, 40 mm diameter dishes, 24-well plates and 20x20 mm cover slips.

    • PrimeCoat elastic substrates require to be coated by the end user to promote cell adhesion.

    • PrimeCoat elastic substrates are transparent. Cells can be visualized with standard transmission light microscopes (e.g., Phase contrast, DIC).

    • PrimeCoat elastic substrates are compatible with most standard molecular or cellular techniques: immunofluorescence, immunohistochemistry, protein analysis (e.g., Western blotting, and RNA/DNA extraction).


    Biomimetic cell culture substrates at reach

    PrimeCoat series combines simplicity and accessibility:
    • simplicity of cell handling

    • straightforward compatibility with cell analysis tools

    • accessible prices

    ExCellness in selected peer reviewed publications

    In the following peer-reviewed publications, ExCellness biomimetic cell culture devices have been used or cited:
    • A. Elbediwy et al.  Enigma protein regulate YAP mechanotransduction. J Cell Sci 2018 131: jcs221788

    • F. Klingberg et al. The fibronectin ED-A domain enhances recruitment of latent TGF-β-binding protein-1 to the fibroblast matrix. J Cell Sci 2018 131: jcs201293

    • B. Liu et al. Increased substrate stiffness elicits a myofibroblastic phenotype in human lamina cribrosa cells. Investigative Ophthalmology & Visual Science February 2018, Vol.59, 803-814. doi:10.1167/iovs.17-22400

    • J. Weldrick et al. A rapid and efficient method for the isolation of postnatal murine cardiac myocyte and fibroblast cells. Revue canadienne de physiologie et pharmacologie, 2018, 96(5): 535-539

    • N Elkhatib et al. Tubular clathrin/AP-2 lattices pinch collagen fibers to support 3D cell migration. Science16 Jun 2017: Vol. 356, Issue 6343, eaal4713

    • Y Attieh et al. Cancer-associated fibroblasts lead tumor invasion through integrin-β3–dependent fibronectin assembly. J Cell Biol. 2017 Nov 6; 216(11): 3509–3520.

    • A Glentis et al. Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane. Nat Commun. 2017 Oct 13;8(1):924.

    • N Vedrenne et al. Isolation of astrocytes displaying myofibroblast properties and present in multiple sclerosis lesions. Neurochem. Res. 2017 Apr 22. 

    • X L Chen et al. MicroRNA-21 preserves the fibrotic mechanical memory of mesenchymal stem cells. Nature Materials 16, 379–389 (2017).

    • MR Zeglinski et al. Chronic expression of Ski induces apoptosis and represses autophagy in cardiac myofibroblasts. Biochim.  Biophys. Acta. 2016 Jun;1863(6 Pt A):1261-8.

    • H Chen et al. Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis. Nat. Commun. 2016 Aug 18;7: 12564.

    • NP Talele et al. Expression of α-Smooth Muscle Actin Determines the Fate of Mesenchymal Stromal Cells. Stem Cell Reports. 2015 Jun 9;4(6) : 1016-30.

    • V Sarrazy et al. Integrins avb5 and avb3 promote latent TGF-beta 1 activation by human cardiac fibroblast contraction. Cardiovasc Res (2014) 102 (3)

    • VF Achterberg et al. The nano-scale mechanical properties of the extracellular matrix regulate dermal fibroblast function.J Invest Dermatol. 2014 Jul;134(7):1862-72.

    • JA Cadby et al. Differences between the Cell Populations from the Peritenon and the Tendon Core with Regard to Their Potential Implication in Tendon Repair. 2014. PLoS ONE 9(3): e92474.

    • T. Grand et al. Aggravation of Cardiac Myofibroblast Arrhythmogeneicity by Mechanical Stress. Cardiovasc Res2014 Dec 1;104(3):489-500.

    • JA Cadby. Can we improve tendon healing in the horse? A multi-angle study of a multi-facet problem. ISBN: 978-90-5335-715-6.

    • A Vashist et al. Recent advances in hydrogel based drug delivery systems for the human body. J. Mater. Chem. B, 2014,2, 147-166.

    • EP van der Veer et al. The RNA-Binding Protein Quaking is a Critical Regulator of Vascular Smooth Muscle Cell Phenotype. Circ Res. 2013 Oct 12;113(9):1065-75.

    • A De Boeck et al. Differential secretome analysis of cancer-associated fibrobroblasts and bone marrow-derived precursors toidentify microenvironmental regulators of colon cancerprogression. Proteomics 2013,13,379-388.

    • C Godbout et al. The Mechanical Environment Modulates Intracellular Calcium Oscillation Activities of Myofibroblasts. PLoS One. 2013; 8(5): e64560.

    • S Constant et al. Colon Cancer: Current Treatments and Preclinical Models for the Discovery and Development of New Therapies. Drug discovery; Editor Hany A. El-Shemy. ISBN 978-953-51-0906-8.

    • JL Balestrini et al. The mechanical memory of lung myofibroblasts. Integr. Biol. 2012,4, 410-421.

    • Stem Cells and Cancer Stem Cells, Volume 8. Therapeutic Applications in Disease and Injury. Editors M.A. Hayat. ISBN 978-94-007-4797-5.

    • A Skardal et al. Bioprinted amniotic fluid-derived stem cells accelerate healing of large skin wounds. Stem Cells Transl Med. 2012 Nov;1(11):792-802. doi: 10.5966/sctm.2012-0088. Epub 2012 Oct 29.

    • A Skardal et al. Substrate elasticity controls cell proliferation, surface marker expression and motile phenotype in amniotic fluid-derived stem cells. J Mech Behav Biomed Mater. 2013 January; 17: 307-316.

    • BJ Crider et al. Myocardin-Related Transcription Factors A and B Are Key Regulators of TGF-b1-Induced Fibroblast to Myofibroblast Differentiation. Journal of Investigative Dermatology (2011) 131, 2378-2385.

    • L Follonier Castella et al. A new lock-step mechanism of matrix remodelling based on subcellular contractile events. Journal of Cell Science 123, 1751-1760.

    订货信息:

     

    Dishes
    Product Code     Description     
    01. 100.002.00     2 kPa culture surface 100 mm ?     
    01. 100.005.00     5 kPa culture surface 100 mm ?     
    01. 100.010.00     10 kPa culture surface 100 mm ?     
    01. 100.015.00     15 kPa culture surface 100 mm ?     
    01. 100.030.00     30 kPa culture surface 100 mm ?     
    01. 100.100.00     100 kPa culture surface 100 mm ?     

    Product Code     Description     
    01. 035.002.00     2 kPa culture surface 35 mm ?     
    01. 035.005.00     5 kPa culture surface 35 mm ?     
    01. 035.010.00     10 kPa culture surface 35 mm ?     
    01. 035.015.00     15 kPa culture surface 35 mm ?     
    01. 035.030.00     30 kPa culture surface 35 mm ?     
    01. 035.100.00            100 kPa culture surface 35 mm ? 
     
    Multi-well plates 

    Product Code     Description     
    04.024.002.00     2 kPa culture surface 24-well plate     
    04.024.005.00     5 kPa culture surface 24-well plate     
    04.024.010.00     10 kPa culture surface 24-well plate     
    04.024.015.00     15 kPa culture surface 24-well plate     
    04.024.030.00     30 kPa culture surface 24-well plate     
    04.024.100.00     100 kPa culture surface 24-well plate 

     

        
    Cover slips

    Product Code     Description 

    03.020.002.00     2 kPa culture surface 20x20 mm c.slip 
    03.020.005.00     5 kPa culture surface 20x20 mm c.slip 
    03.020.010.00     10 kPa culture surface 20x20 mm c.slip 
    03.020.015.00     15 kPa culture surface 20x20 mm c.slip 
    03.020.030.00     30 kPa culture surface 20x20 mm c.slip 


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