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    bpsbioscience,50272,BCL-2, His-tag
    bpsbioscience,50272,BCL-2, His-tag
    • bpsbioscience,50272,BCL-2, His-tag

    bpsbioscience,50272,BCL-2, His-tag

    产品报价:询价

    更新时间:2019/2/19 16:35:28

    地:美国

    牌:bpsbioscience

    号: 50272

    厂商性质: 生产型,贸易型,服务型,

    公司名称: 北京容圣科技有限公司

    产品关键词: SARM1 FLAG-Tag   Caspase6 His-tag   BCL-XL   His-tag  

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    Species: Human
    Host Species: E. coli
    MW: 27 kDa
    Genbank #: P10415
    Tag(s): C-terminal His-tag
    a.a: 1–211
    Background:
    Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
    Description:
    Human Bcl-2 (GenBank Accession No. P10415), a.a. 1-211 with C-terminal His-tag, MW = 27 kDa, expressed in an E. coli expression system.
    UniProt
    P10415
    Synonym(s):
    Bcl, Bcl2, B cell lymphoma 2
    Assay Conditions:
    Following the protocol for BPS Cat. #50222. Briefly, BCL-2 was combined with BCL-2 peptide ligand in TR-FRET assay buffer along with anti-His Tb donor and dyelabeled acceptor. Varying concentrations of ABT 199 were added and the reaction was incubated at room temperature for 2 hours followed by fluorescent intensity measurements.
    Formulation:
    40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 200 mM imidazole
    Format:
    Aqueous buffer solution
    Application(s):
    Useful for the study of apoptosis, screening inhibitors, and selectivity profiling.
    Reference(s):
    1. Labi V. et al., Cell Death Differ. 2008 Jun;15(6):977-87.
    2. Rong Y.P. et al., Mol Cell. 2008 Jul 25;31(2):255-65.
    Warning(s):
    Avoid freeze/thaw cycles
    Scientific Category:
    Apoptosis
    Product Type:
    Recombinant Protein

     

     

     

    目录#尺寸产品名称
    50272100微克BCL-2,His-tag
    50273100微克BCL-XL,His-tag
    100077100微克BCL2A1,His-Tag
    100080100微克BCL2L10,His-Tag
    100091100微克BCL2L2,His-Tag
    80500

    10微克
    50微克

    Caspase3,His-tag
    80113

    10微克
    50微克

    Caspase6,His-tag
    70000

    10微克
    50微克

    Caspase7,His-tag
    80114

    10微克
    50微克

     

    Caspase8,His-tag
    8011550微克Caspase9,His-tag
    40742100微克MCL1,His-Tag
    801175微克NLRP3(NALP3),His-FLAG标签(Sf9衍生)
    100069100微克SARM1,FLAG-Tag
    7500320微克STAT3,GST-tag
    8001650微克WDR5,His-Tag,Biotin-Labeled
    7500250微克XIAP(Bir2,Bir3),His-tag
    7500150微克XIAP(Bir3),His-tag
    8040120微克XIAP,FLAG-tag

    北京容圣科技有限公司

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    手机:18611717737

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