• <div id="y09gn"></div>
  • <li id="y09gn"></li>
    <dl id="y09gn"></dl>
    <div id="y09gn"><s id="y09gn"></s></div>
    来宝网Logo

    热门词:生物显微镜 水质分析仪 微波消解 荧光定量PCR 电化学工作站 生物安全柜

    山东博科
    现在位置首页>实验试剂制品>干细胞>干细胞试剂盒>bpsbioscience,79590,Cathepsin B Inhibitor Screening Assay Kit
    bpsbioscience,79590,Cathepsin B Inhibitor Screening Assay Kit
    bpsbioscience,79590,Cathepsin B Inhibitor Screening Assay Kit
    • bpsbioscience,79590,Cathepsin B Inhibitor Screening Assay Kit

    bpsbioscience,79590,Cathepsin B Inhibitor Screening Assay Kit

    产品报价:询价

    更新时间:2019/2/19 16:30:44

    地:美国

    牌:bpsbioscience

    号: 79590

    厂商性质: 生产型,贸易型,服务型,

    公司名称: 北京容圣科技有限公司

    产品关键词: 筛选检测试剂盒   Assay Kit   抑制剂筛选检测试剂盒   Inhibitor Screening Assay Kit  

    28
    访问人数
    0
    累计评论


    Background:
    Cathepsin B is a cysteine protease that primarily functions as an endopeptidase within endolysosomal compartments in normal cells. High levels of cathepsin B are found in a wide variety of human cancers and in experimental models, such as transgenic models of murine pancreatic and mammary carcinomas, causal roles for this protein have been demonstrated in initiation, growth/tumor cell proliferation, angiogenesis, invasion, and metastasis.
    Description:
    The Cathepsin B Inhibitor Screening Assay Kit is designed to measure the protease activity of Cathepsin B for screening and profiling applications. The Cathepsin B assay kit comes in a convenient 96-well format, with purified Cathepsin B, its fluorogenic substrate, and Cathepsin buffer for 100 enzyme reactions. In addition, the kit includes the cathepsin inhibitor E64 for use as a control inhibitor.
    Materials Required But Not Provided:
    • ? 0.5 M DTT in aqueous solution

    • ? Adjustable micropipettor and sterile tips

    • ? Fluorescent microplate reader

    Synonym(s):
    Cathepsin B, CTSV, Amyloid Precursor Protein Secretase, CTSB, APP Secretase, activity assay kit
    Supplied As:
    The Cathepsin B assay kit comes in a convenient 96-well format, with purified Cathepsin B, its fluorogenic substrate, and Cathepsin buffer for 100 enzyme reactions.
    Format:

    COMPONENT:

    Instructions for use:
    See assay kit data sheet for detailed protocol.
    Storage / Stability:
    Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.
    Application(s):
    Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
    Reference(s):

    1.  Aggarwal, N., & Sloane, B. F. (2014). Cathepsin B: multiple roles in cancer. PROTEOMICS– Clinical Applications  8(5-6), 427-437

    2.  Siklos, M., BenAissa, M., & Thatcher, G. R. (2015). Cysteine proteases as therapeutic targets: does selectivity matter? A systematic review of calpain and cathepsin inhibitors. Acta Pharmaceutica Sinica B5(6), 506-519

    Warning(s):
    Avoid freeze/thaw cycles.
    Scientific Category:
    Protease
    Product Type:
    Assay Kit

    北京容圣科技有限公司

    | 第6

    手机:18611717737

    联系人:程园

    电话:010-57218832

    传真:010-57218832

    QQ:631767688

    (联系我时,请说明是在来宝网上看到的,谢谢!)


    云南11选5技巧
  • <div id="y09gn"></div>
  • <li id="y09gn"></li>
    <dl id="y09gn"></dl>
    <div id="y09gn"><s id="y09gn"></s></div>
  • <div id="y09gn"></div>
  • <li id="y09gn"></li>
    <dl id="y09gn"></dl>
    <div id="y09gn"><s id="y09gn"></s></div>